This question was submitted via our Ask a TMS Therapist program. To submit your question, click here. Question Hello, Dr. Schubiner told me that: "It is almost the norm for TMS to start as a physical injury. Then the danger signal in the brain is set off and pain occurs. Then the brain/body learns that pain as a neural pathway. Then the injury heals, and then either the danger signal turns off or it doesn't. If the danger signal is still "on", then pain continues and/or migrates. In people who have sensitized brains from trauma, any physical (or emotional) injury can activate the danger signal and cause persistent pain." My question is: How do I turn off the danger signal associated with the pain?