This question was submitted via our Ask a TMS Therapist program. To submit your question, click here. Question Hello, Over the past year I've noticed I've developed pain when sleeping on my stomach, and it began as soon as I moved to another city to start grad school. At first I thought I just needed to adjust my sleeping position or get a new bed, but now, a year later, I have back pain and severe stiffness that wakes me up in the middle of the night no matter what I sleep on or what position. All of a sudden I'll be sleeping and turn off and get woken up be severe stiffness and pain. I never have back pain in the day when I'm up and moving around, so it goes away as soon as I get up and move around after about 10-15 minutes. I went to a rheumatologist and she ruled out lupus; she thought it might be an inflammatory condition, and so far has done one blood test testing for an inflammatory gene that's present in about 80% of cases with my symptoms and I was normal for that. She wants me to do an X-ray and possibly MRI to see what's going on with my spine. I've read a lot about TMS and back pain and know that even abnormal scans can still be TMS, but I'm puzzled as to why I only have this pain and stiffness when I'm asleep, as I would imagine that's when you're most relaxed? I've read a number of things that say pain during sleep points to an autoimmune/inflammatory condition. I also don't think it's any coincidence this pain started literally the week I started grad school, and grad school does cause me a significant amount of stress and conflict, but having awareness of that doesn't seem to make the pain go away so now I'm not so sure if it really is stress or something more serious. I'm just curious if there's any way this could be TMS? Thanks!