I was diagnosed with epididymitis 9 years ago (right testicle only) and after multiple courses of anti-biotics, anti-inflammatory meds, loads of different doctors and even more specialist urologists appointments I came to the realisation; this probably isn't going away. For anyone who doesn't know what epididymitis is, Epididymitis is an inflammation of the coiled tube at the back of the testicle. Over the years it turned into Epididymo-orchitis, which is the same but the testicle is also swollen It's pretty nasty, and really uncomfortableu it also makes me need to urinate frequently. About me, I've always had a severe anxiety disorder (GAD, SAD), I was an anxious child with select mutism and I'm now an anxious adult, with some depression and stress, sometimes my anxiety mutates into anger but for the most part I'm not doing too bad. I first noticed my testicle inflammation was linked to my brain when my boss at my previous job shouted at me in front of my colleagues, I got really embarrassed / stressed and my testicle flared up, and gave me crippling pain. After this event I noticed that my testicle is always worse when I'm anxious or emotional about something. For the most part, it stays settled these days, when I say settled I mean there is still something wrong with it but it's not painful or causing any issues, it's just waiting to flare up. The wierd thing is, it flares up when I take drugs, the drugs I've noticed do it are... Nicotine (quit now) Caffeine (quit now) Sertraline (currently started taking last week) Citalopram Viagra (only 27 but struggled with ED since 21, lowish T) Cialis Cocaine (haven't took in years, used to self-medicate for my mental health) Mephedrone (same as above) Which, is basically every drug I've ever taken. What gives? Anyone else experiencing similar symptoms? I have never been diagnosed with TMS, just self-diagnosis, a therapist I was seeing said it's not a real thing and my doctor(s) are skeptical, too.